Hello everyone :thumbup:, I am a PhD student at Columbia University and need some photography help. My project involves using yeast as a model to study human cancers. Part of the project involves conducting high-throughput screens on rectangular agar plates. When the screens are finished we use to scan the plates into the computer (with a high end flatbed scanner) in order to automatically analyze them. However we would like to instead take pictures of our plates with a digital camera as it is faster and reduces glare. The current setup involves placing the plates on a light box, mounting a digital camera on a stand 1-3 feet above the plates, and quickly snapping pictures. The problem I am currently facing is a fisheye effect (see attached photo). In order to automate the analysis process there can be no fisheye. How can I reduce this effect? Also, we would like to reduce vignetting as much as possible. Right now i am using a crappy Canon Powershot, but my lab is willing to upgrade to any camera required to make this work. I know nothing about photography, but am eager to learn and would really appreciate any suggestions. check out a sample picture at http://www.rothsteinlab.com/graphics/P1040447.JPG (2.5 mb) Thanks!