I've had Panasonic mirrorless, Olympus mirrorless and now Fuji mirrorless ... none of them were particularly uncomfortable. But then how a camera feels is not an important criteria for me for purchasing a camera. Having my right hand ... or any hand tied up ... I think is a bad thing. At a minimum, it would make changing lenses difficult and slow. As I tend to shoot with two cameras, it makes switching cameras somewhat problematic. Despite the S-curve shape, I'll keep my neck and sling straps. Another item I won't get is their Quick Draw Camera Holster ... purely on aesthetics, or lack thereof.