I use a combo of the spot healing tool and check the " created texture" button to remove blemishes and unnecessary wrinkles, and then i go over the whole face with the blur tool. Makes them look flawless and, keeps the realistic look. Plus its quick and there is no need to make new layers and such. A before pic, and what you have done so far would help us out a little.
If you would like, you can send it to me at [email protected].
Otherwise, I don't see how anyone could help you with a non descript photo.
Best of luck to you.
I always make a copy of the background layer and after that work on copies of the copy, just to be on the safe side. After working on the skin with the healing tool or whatever techniques you are using on the copy layer just lower the opacity on that layer and that's it.