Don't fear ISO, but don't make it a basic adjustment. Adjust exposure with shutter speed and aperture, and adjust ISO if you can't get the shutter-speed/aperture settings in the range you need.
Look at the shot and decide what's more important. Is a certain depth of field your desired result, like blurred background/sharp subject? Or the opposite: everything sharp all the way out, like a landscape. Or are you shooting action and trying to stop motion? Or maybe you want to show motion in your image with a little blurred movement?
Making those decisions tells you if aperture or shutter speed is more important. Blurred background/sharp subject means large aperture (small f-number.) Landscape means mid-to-small aperture (large f-number.) Freezing motion means fast shutter speed, and incorporating motion means slow shutter speed.
Shooting 20 pictures in AV at different ISOs is........ silly. Changing the ISO simply changes the shutter speed picked by the camera according to the aperture you used.
Unless I read your question wrong. I read it as shotgunning the settings and hoping something came out right. You might have meant testing the settings and comparing the results. In that case, not so silly.
But my first sentence still applies. Decide on an ISO based on what you expect for a light level. Full daylight outdoors you don't need more than ISO 100 unless you have to have hyper-fast shutter speeds
and smallish apertures. Late afternoon, or cloudy skies, you should think about 400 or 800 for ISO. But once you have an ISO, leave it. Use shutter and aperture to get what you want.
Now think about me learning photography some number of moons ago with my dad's manual Voigtlander, a handheld light meter, and Kodachrome 25 film..... No screen to look at, and no data recorded. Yeah, it's rough these days!!!!
