well...actually everything is relative. you do not need to change your iso setting! with digital, keep it at 100.
so long as your exposure remains the same, you can use any combination of shutter speeds and apertures. you just have to remember, that when you change one, you must change the other in the opposite direction.
if you increase your shutter speed, you have to use a larger aperture. conversely, if you decrease your shutter speed, you have to use a smaller aperture.
for example, 1/250 @ f2.8 is the SAME exposure as 1/15 @ f11.
f2.8 - f11 = 4 stops down
1/250 - 1/15 = 4 stops up
so let's say you meter your subject at 1/125 @ f8. you want to use a slower shutter speed to capture motion. let's say you pick 1/15, which is 4 stops slower. you would then need to adjust your aperture to f32, which is 4 stops smaller than f8.
now, if you want to capture motion (as opposed to freezing it) in your photographs, during the daytime you won't need to use anything slower than 1/2 second. at night, if you want to capture traffic trails, you will be able to use 20 seconds and slower.
sean