Welcome to TPF.
Your photo is pretty good for starting out. It could be a little sharper; the 1/100 sec. shutter speed is likely to blame -- you've got a little camera shake. Tone response is OK -- it's flat lighting and you could use a contrast bump and corner burn to counter that. There's a cyan color cast over the photo which is most likely just your camera's auto WB algorithm (they don't work). Don't know if you found the scene as is or if you did some fiddling with it. Couldn't help but notice that the water drops are only on the green leaf Why no water drops on the brown leaf?
Questions 2 & 3: buy a macro lens.
Question 1: That sounds pretty boring. Try this instead:
As you take photos you have a number of goals that you want to reach that will give you the best possible final result. The game you have to play is that given circumstance you'll have to sometimes compromise one or more of those goals for the sake of one of the other. Ideally you want to reach them all but circumstances may not allow that and different goals will shift priority depending on what you're photographing. Here's the three big ones that involve the "settings" you mentioned.
Goal One: Set you camera ISO to 100. That's base for your camera. The goal is to fully expose the sensor in your camera. Exposure is a function of the intensity of the available light + shutter speed + f/stop. You will get the best photo when you achieve this goal of delivering to the sensor the full amount of light that it can handle. HOWEVER: as in the photo you took above you must at times compromise this goal. When you must, you must --
get the photo. It wasn't bright enough when you took the photo above and to get the 1/100 sec. shutter speed, which was shaky, and so you had to cut over 3 stops of light to the sensor (ISO 1000). Your photo was taken then utilizing less than 1/5 of the sensor's recording capacity.
Goal Two: A sharp photo. This is one of those cases where it's what we want 99% of the time. Photos that aren't sharp can be fabulous but those are usually not the ones that suffer from camera shake. This then is about shutter speed. In your photo above I assume you hand-held the camera. Even 1/100 sec. wasn't quite fast enough. You let this goal take precedence over Goal One. That's the right choice. When you need the faster shutter speed you need it. And it's not just about hand-holding a camera. How about photographing a tennis match or a soccer game. Here you see then where we have to make compromise choices about which goal gets priority. In your photo above the subject wasn't moving. A tripod would have allowed you to take a sharp photo at a slower shutter speed and satisfy this goal and Goal One.
Goal Three: Normally we want the subject of our photo to be in focus and we want to render a pleasing
DOF for the subject (Depth of Field). This is the f/stop in the lens. Now go back up where I defined exposure for you in Goal One: Exposure = available light + shutter speed + f/stop. There are three variables there that you have control over if not directly at least indirectly. F/stop is the aperture in the lens and it opens and closes letting more or less light pass to the sensor. At the same time it controls the rendition of DOF.
You can control the lens f/stop (it effects exposure and DOF).
You can control the shutter speed (it effects exposure and rendition of motion -- yours and subject's).
You can control the available light sometimes (add more with flash for example or wait for the sunshine).
Those are the big ones. There are secondary concerns like color. For example I said your photo above has a cyan cast. You'll need to learn metering and exposure control. You don't want to over or underexpose your photos. Look into the EC (exposure compensation) control on the camera. Your camera has a sophisticated auto focus system which you need to understand and learn to use.
And when you get past all of that there's always the raw versus JPEG choice.
Best new camera user tip ever: Establish a set of defaults for your camera. For example set base ISO, set P mode, set single point AF, set center average metering, set auto WB, etc.. and memorize those defaults. NEVER turn your camera OFF without making sure those defaults are set.
Joe