There's an almost infinite number of variables such as your specific subject, what light levels you're actually shooting at, the background, if there's shadowy areas or not, etc. I have ISO1600 shots of off of my D80 that look perfectly clean, and then some iso400 ones that actually look pretty gritty, all depending on what I happen to be shooting and how I'm shooting.
"Generally" if the light level is reasonable and you're just trying to maintain a faster shutter speed, high ISO will tend to look a bit cleaner. If you're down in the gutter with no light and a longer shutter speed, high ISO will "tend to" look worse here. That all depends on everything above though too. The subject, specific exposure, etc.