What a cutie.
The one thing that stands out to me, that would make it a better photo, is if she were looking at the camera. That helps to create a connection to the viewer, making it a more 'effective' portrait.
The usual problem we have as parents and photographers, is considering what the casual viewer will think/see. You were there (taking the photo) so you probably have a good idea of what she was looking at. You are her (mother?) so you know her personality and that look/expression probably has a lot of meaning to you (you probably know what she was thinking).
A causal viewer doesn't know what she may be looking at or what her personality is like. So in that sense, there is a disconnect between the subject and the viewer.
If you want to create strong, successful portraits...it usually helps if the viewer does have a connection with the subject. One was is to have the subject looking at the camera but another way is to have the subject looking or interacting with something tangible. The issue here is that she's interacting with something that we don't know. This can be used to add mystery to the portrait...but I don't think that you're going for mysterious here.
And of course, you may not even want or need to have that connection from subject to viewer. If this is just going to be a personal family photo, where all the viewers will know her...then it's not so important. But as a formal portrait goes...I think it could be better with that connection.
You probably knew this...and are just wanting to tell me that "she's a kid, YOU try getting her to look at the camera".

My twin daughters won't so much as acknowledged my presence when I've got a camera in hand. :roll:
As far as the lighting goes, it's a little bit confusing in that the light that we see in her eyes is from our right, but the brighter side of her face is on our left. Another way of putting it, would be that the catch lights are from the 'fill' light. That's not the worst thing in the world, but it's usually not as good as the catch lights showing up as reflections from the main/key light.
You may have intended the light on your right to be the main light...and in some sense it is, as we can see a shadow to the left of her nose. But the light on your left is then too bright IMO. It works great on her hair, but that whole side of her face is getting to be too bright.
What I'm thinking would be to bring the light on your right, in closer to her. Making it softer and brighter on her. Then move the light on your left, a little higher and further back so that it's mostly lighting up her hair, but not so much the side of her face.
Again, I know...kids: they don't tend to sit still for precise portrait lighting but since you asked for C&C...
