Hello there! My first post here and I am seeking help. - My JPEG photos are shot in 3872x2592, fine mode. Average photo size is 3,80MB - Camera is Nikon D80 I have to edit my photos using Lightroom and photoshop to then upload them on a website as JPEGs; a standard of 300dpi, 8 bit per channel, RGB JPEG files that are at least 15inches/38 cm high (4500) pixels. Now how can I save a JPEG after editing series without losing much data and size, admitted that size affects resolution? Is saving my jpeg photo as tiff at the end of the first editing so I can perform as many editings I want on the same photo before finally saving as jpeg a good thing to do? Can I forget about tiffs and just save as jpegs while editing? I also have to switch to Picnik.com for editing after editing with Lightroom and Photoshop but in Picnik.com I can't work on my tiffs because the website accept only files inferior to 16 MB while mine are an avergae of 28MB so on Picnik.com I can only save as JPEG and I want to do it without losing much data. When i save there as jpeg my photo size drop to an average of 980 kb (original size 3,80mb) In the photoshop CS3 "image size" box, I apply 300 to resolution, 4500 to height, keep "scale Styles","Constrain Proportions","resample Image" checked and select "bicubic(best for smooth gradients)", When I save as jpg there the size increases to an average of 4,30 MB but I wonder how much data was lost in all the editing processes and if my photo would still be good for large prints. Thank you very much for your assistance!!!