Well, use the spot meter as a probe. Ideally, you should point it at the brightest spot where you want to see detail and get a reading. Say it is 1/1000sec at f/8 at ISO 200. Then you see what the darkest spot reads. Say it is 1/4 sec at f/8 at ISO 200. That means that the lightest and darkest parts of your image are about 8 stops apart. Now meter something in the scene that is at the midpoint of brightness. It might be 1/125sec at f/8 at ISO 200. Chances are, if you go to evaluative metering for this scene, you'll get something close to 1/125sec (f/8, ISO 200). Now you know that your highlight is about 3 stops above the midpoint, and your detailed shadows are 5 stops below the midpoint. For most DSLR cameras, the image will be within the dynamic range of the camera, and you will get detail in both the highlights and the shadows.
However, suppose the highlight read at 1/4000 sec, everything else being equal (ie, two stops brighter). Now, your camera may not be able to extract detail in the highlights as they risk being "blown". So as a photographer, you make the decision about what is more important to you - the highlight detail or the shadow detail, and bias your exposure accordingly. It should also be clear that the exposure will be set manually because you are overriding the reading that the camera makes and you set an intelligently-derived exposure that will give you the photo you want.
The exception to the above is when the point of interest is very small (relative to the size of the frame), and the exposure of that point of interest has to be right - then I will go with the camera's reading on that spot. An example of this would be shooting a performer on stage, lit by bright floodlights, but surrounded by black (or very dark) background. The spot reading on his/her face would give me a much better exposure reading than an "evaluative" or averaging reading. The same applies if you are shooting a person surrounded by very bright background (snow or sand), and the averaging exposure will usually drastically underexpose the person.