The issue with interstellar travel is the time it takes to get places. In our case, and with the speeds we'd be able to put together, any interstellar travel will either be multi-generational, or using some form of suspended animation. However, if the sentient species has the ability to live much longer, say, 10,000 years, then the travel time becomes less of an issue. Fact is, there's much more we don't know - everything we see and sense (normal matter and related photons) makes up less than 5% of the universe, and we don't have a complete handle on the part that we do sense. It wouldn't surprise me if there's some civilization out there that has figured out how to manipulate dark energy and use it. The "ultimate" speed limit applies to travel through space by photons and matter, but does not seem to apply to space-time itself. So, there's a wrinkle that we still have to discover.