Usayit, I tend to stay in Matrix unless there is something in the frame that I want to bring out by nailing the exposure on it.
I also use the spot meter to scope out a room if I'm going manual with the intent to batch process.
You?
On my 1 series SLR, I tend to stay in either Spot with the camera in either P or Av (usually Av) depending on my "mode of thought": Either thinking in terms of Aperture or thinking in terms of shift. On my other SLRs (Elan IIe), I'll leverage center weighted. These two modes plus center focus point provides a nice balance between control and automation. I can explicitly focus on a point, explicitly select metering point, and maintain control over final exposure.
NOTE: I went from a 10D and ElanII to a 1v and 1d MarkII (both used). One of the biggest reasons for this decision was the "multi-spot" metering in the 1 series camera. I cannot stress how important this feature was for me. NOTHING and I mean NOTHING in the Canon line meters with such control and precision. You leverage the spot meter to record up to 8 points/readings and the camera evaluates and marks the recommended exposure. In a pinch, you take readings in dark shadows and bright highlights... details in both are maintained just like magic. There was a push to "upgrade" to the 5D when it came out... but people just don't understand that there is a lot more to a camera then the sensor and processor. If it wasn't for the 1 series, I would just stay in center weight metering. The camera is WELL past the typical DSLR life span.. but I see no need to move to anything else.
The other option which I used for many years was simply a handheld meter with the camera in manual. In part because a lot of my cameras had no meter or any type of automation. I still find myself doing this anyway simply because I enjoy it. Often I'll walk the streets of NYC (for example), pull out my handheld meter, and take an ambient exposure reading over my shoulder. I set the appropriate shutter/aperture and just simply shoot.... and focus on shooting... If I shoot into an area of brighter sunlight, I'll stop down a stop or two. If I shoot into an area that is dimmer, I'll open her up a stop or two. Simple as that.... just taking "baseline" exposure readings every-once-in-a-while with my handheld. You guys should try it sometime.... Spotmatic, handheld meter, B&W film, 35mm and 50mm lenses..... it is truely liberating (from the wizbango techno gadgets).
When things get too fast, I will switch to P, Matrix mode, and activate all the focus points the camera (whopping 45 points in the 1 series). I don't do this for a living and I am far from a all-star photographer... I will be the first to admit I need help from the camera's automation. If someone sees this as not "earning" my badge of photographic honor, they can shove a sock in it.
They are freakin tools... not badges of honor or proof of strength of skill. The real strength is knowing all the adv/dis of each tool in the box and knowing how to leverage all of them.