All of my enlarger lenses 80mm and less have the same lensboard hole size. It's just a matter of unscrewing the retaining ring, and switching it out.
The B-22 is a nice enlarger. I'm not sure about how the condensers work with that model. I have an Omega D-2 that came with condensers for 35mm and 4x5. I just leave the 4x5 ones in all the time, and it works fine. I think you'd have a light fall-off problem doing larger formats with smaller condensers, but the other way around shouldn't be a problem. You'll just have to try and see. On my Beseler 23C you adjust the lamphousing closer or farther away when switching from 35mm to MF. The B-22 may have something like that.
The componon is top of the line Schneider.