I haven't used a v300 myself; I use a v700. From what I've read on other forums and seen posted, the v300 is a very good value. Whether its "any good" depends largely on the use you have for the images and what type of negatives you will be scanning.
Certainly, for anything that will only be displayed electronically (web, digital frame, ...) is as good as you need. Even for high quality printing, it should be quite adequate when scanning color negatives. Some slides and very long tonal range B&W negatives may challenge the v300's ability to retain deep shadow and light highlight detail at the same time but this type of detail is rather invisible on electronic displays. It would show only on very carefully made prints from the best high-end printers.
The EPSON Scan software that comes with the v300 is the same as ships with all of the EPSON scanners, such as my v700. Its very decent software, though I recommend that you explore the "Professional Mode". The other simpler modes have somewhat limited control.