When your in-camera noise reduction is on, processing your photos will take much longer (well, considerably much), so your camera will not be ready for the next photo so soon. So I suggest you leave it off. You can always filter your noisy pics with software later. Oftentimes, noise is less visible in a print than it is on the screen (given the print is small enough). But you might need your camera to be ready fast!
But I guess the 1000 ISO was too high for this pic. It doesn't look all in focus. Something is there (next to the noise, which is most visible in the wall behind him) that looks like a technical flaw. Look at the light spots in his eyes. They are not sharp. Nor is his hair or rim of ear. There seems to be some camera shake, yet the lit part of his face is sooo bright (which is often called "hot" or "blown").
As to how to best POSE people I know NOTHING and must reverentially listen to the advice of all those who have once learned some about it.