I think the girl is too well dressed to give a 'down and out' feeling to it. Knowing nothing about New Orleans, I just see this as a nice composition of a pretty girl looking at a pretty city on a clear night.
I like the general composition and idea, and I also like the edit by dsiglin.. particularly the addition of the 'light blue overlay' which adds a nice ambiance to the image.
I think the original image could benefit from removing a small chunk of the foreground grass, similar to the amount dsiglin cropped off, I think there's just a bit too much foreground than is necessary, and removing it will also enhance the panoramic feeling the image already has, which I like.
I find the water tower mildly distracting, but I think it also helps balance out the composition adding some weight to the right side, so I'd probably keep it in..