Depends on the specific camera and its AF system. Many times, in marginal/difficult conditions, I will select a group AF point scheme, one that uses more than one but less than a dozen out of 51 AF points. FOr example, indoors, when focusing a slower zoom lens and using an off-camera flash, I will use a Group Dynamic AF system so that I can get faster, more-sure lock-on with a "slow" lens, like an f/3.3~4.5 zoom lens. Also, with fast but longer lenses like the 50/1.,8 or 85/1.8 indoors, also using off-camera flash, I find that using more than one AF point means I do not have to focus/recompose, but can simply usew the 4-way controller on the back of the camera, and shift the AF to the area I want, and the camera can easily focus even in very bad light.
For focusing on really fast-moving stuff, I prefer a group AF approach. It gives the computer more than just one,single AF point, and eliminates the opportunity for that one,single AF point to get a No DATA response when it lands on a flat-toned subject. It's kind of like the difference between one-eyed vision, and binocular vision...