Help with maintaining detail in dark/white shots

[fmw]

Maybe I'm mistaken but I seem to get more realistic color (and detail in the dark) if I keep the ISO down, especially in the dark reds, and blues. Maybe if I went up one F stop, go with a slower shutter speed, and still maintain the slower ISO? Or would it be better to go up on both shutter speed and F stop, and add fill light? Trying to get to the sharpest image with the least amount of noise and most vibrant/realistic color.

I agree with you. I would shoot this image at f16 or f22, ISO 100 and use a tripod.