For your question about settings I recommend getting a light meter. I use a sekonic that wirelessly triggers my strobes. When shooting with strobes I set my iso to 100 then adjust my aperture based on the lens I'm using and the depth of field I want. This always gets me in the ballpark to start with.
Equipment is always a personal thing especially lens and light choices. Speedlights will probably get you what you need as far as lights go. Lens choice, try working with what you already have. If you don't like it then start identifying what you don't like.
The strobist website gives great info for beginners in off camera lighting. I started with info from that site many years ago and it really helped me get up to speed.