As mentioned before........
Only you can know what that is... If all you are doing is making 'proper' exposures, throw it in program, aperture or shutter priority and rock on. Manual mode is for creative exposure or tricky situations that the auto settings may not get right. It's not a secret magic mode that makes photos better once you learn how to use it.
Next Q is what are you shooting?
I mostly shoot weddings and for such I need to freeze action so the shutter speed is anywhere b/n 1/80-1/200 of a sec. Next step is the ISO - if I'm outdoors it would be low and if i'm in-doors it would be higher. last but not least is f-stop - it would be set properly expose the scene w/ given shutter speed and iso.
So to be a bit more clear, let's say I'm outdoors on a somewhat sunny day that is pretty directional - ISO 200, 1/160sec, f/8 if facing the sun that is behind my subjects (i get a nice silhouette) and f11 if the sun is behind me light the subjects as my flash would.
If i'm indoors, my room lights give me about 5.6-8 on the floor/background, while my on-camera flash and assistant's flash together will give me directional light at about f/8 ( maintaining iso 400 and 1/125 sec).
When I'm in my studio shooting portraits or even products, ISO 200, 1/200sec (i want to eliminate all ambient light possible) and adjust aperture to give me optimal exposure: I'll work with f/8-11 for people (kids like to move closer to light so I'll stop down at those times) and for product will be at f/11-16 depending on what product.
Now if I want specific look at either one of the cases, the numbers above will change.
hope it helps.
good luck
joe