It is certainly worth doing with one flash, often, you won't need any more.
You can't use Canon's wireless system unless you buy a 'Master'. The 430EX can only be a 'Slave' in that system. A master could be a 580/550EX or an ST-E2. Either way, it's not cheap.
You could go with a radio trigger system, which doesn't have the advantage of E-TTL metering, like the Canon system...but it's a more reliable way of triggering a flash.
There is a cheap radio trigger that is supposed to work with that flash...the Cactus V.2. I have this and that flash, and I can tell you that it doesn't work very well. It fired about 60% of the time and often fires twice.
The preferred product is made by Pocket Wizard. These will fire your flash, every time, with a range of 1600 feet (or something like that). You can even fire your camera remotely.
They are not cheap though. You will need two 'transceiver' units and they are just under $200 each.
You could also look at something like the Skyport system from Elinchrome. A bit cheaper than Pocket Wizards but maybe not as reliable when you don't have good line of site.
Personally, I use my 430E on the camera (or on a bracket with off-shoe cord) and use cheap off-brand flash units for off camera use.