I have the Sinking Barge backpack in it goes: 15" Macbook Pro, Canon 40D, 28-70mm L, 50mm 1.4, 28-135mm IS and 17-40mm L. Hoods for all lenses, memory cards, memory card reader, 2 extra batteries, charger and other misc cords/cleaning supplies.
All of the above except for the laptop goes into a previous generation 7 Million Dollar Home, it's a messenger bag.
The other Crumpler I have is the Considerable Embarrassment, which is basically just a case for my laptop when I don't need all my photo crap. One important thing to note is I don't have any really long telephotos like the 70-200mm L, so if you've got one of those you might want to look into the Wickney and Cox as it supports more lenses/bodies.
Check out their website, it's has videos and dimensions etc.