I use Noiseware Pro. I tried the demo first and its really great software. I still don't know how to really fine tune images; there are a lot of advanced adjustments if you want to use them.
The full version of and the Pro version are both reasonably priced, Its been a while, but I think you have options to buy just the standalone program, the photoshop plugin, or both. One benefit of pro, is that it lets you work on 16 bit images.
Just a side question, Because noise reduction can have a significant effect on sharpness, do you guys sharpen in you noise reduction software, or do you still sharpen in you image editor?