Can only corroborate Derrel's take. The F4 was probably the best manual focus camera Nikon ever made but it's a relic. The F5 might best be seen as Nikon's last serious film camera in the F tradition: interchangeable finders, lots of accessories, premium pricing and build quality. The F100 seems to be one Tin a long line of sweet spot feature/ price cameras that punch way above their weight, much like the earlier N90s/F90x and current digital D7200.
Think you missed the point--and the irony. The F4 was an abysmal AF body, especially compared to the far better contemporary N90s/F90x. But as a MF body with knobs and dials. metering options, and no menu-diving, it was great, especially for macro work. I just don't consider the F/F2 to be all that different from other 60s/70s MF bodies.
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I think you missed the irony of your post. The F4 was the first professional 35mm body to offer auto focus in 1988. Of course it is not going to be on par with current AF systems. Here some more irony for you. The first digital SLR was built by Kodak with a Nikon body. I know it's hard to believe but digital sensors have improved from that first DSLR.
As for the F/F2's, the Nikon F was the first true SLR as we know them today. Almost all of the other 35mm SLR's prior to the F had various lack of functions, suck as a mirror that did not return to it's place until you wound the film and auto diaphragms. The Nikon F redefined 35mm SLR cameras by putting it all together for the first time. The F was world renowned for it's innovations and durability. The F2 upped the anti with it's refinements along with the photomic line of viewfinders becoming the epitome of an 35mm SLR system.