Negative space is generally used used as "looking space" or the space an object (car, air plane, etc.) is moving into. In a commercial application it's used for text placement. In this case, there's no reason for it, and it visually unbalances the photo.
The slashy selective color also detracts. I want to know what color eyes she has, how red her lips are, etc. Instead I find my eyes being pulled all over the place while trying to look at a nice looking young lady.