I've traveled a lot and I've lived in two other countries other than the States. I'd move abroad again in a heart beat, but not to some of the places that I would have been willing to live even just 10 years ago. At one point I almost transferred to Helsinki and I still regret that I didn't. If circumstances were right, I'd move there before I ever live in Florida again. No offense to you Floridians. It just doesn't suit me (I was there for 3.5 years.) I need at least one cold season and some hills!
I also applied for a transfer to Kuala Lumpur, but I would never choose that now. As I get older, I get less tolerant of certain things that used to bother me less, so for example, I would now shy away from very congested urban areas, for example. I already don't like being in crowded places here in the States and I'm no longer willing to deal with that PLUS being a foreigner at the same time. It takes a lot of energy to be a foreigner.
If it's important enough to me to live abroad again, I can do it pretty easily. I don't have kids, I don't have a business, I own almost nothing. I have extensive training and experience in teaching ESL and could get a decent job easily in any country. Legally, even! (I have dual citizenship and an EU passport, so I can work there easily whereas someone with only American citizenship might have more problems getting a work visa.) I'm good with languages and am comfortable in other cultures.
At this point in my life, I'm content to stay where I am, but if my situation changed and I found myself with few ties to my current location, there would be a good chance that I'd move back to Europe and do my travels from there.