There are several issues here. The stray hairs (as mentioned), the bright highlight on her nose and left don't really look natural, since there are no highlights in her eyes corresponding to a light source that would cause those highlights. The lack of DOF renders parts of her soft, in a way that (IMO) detract from the image. She is also appears to be wearing contacts... I would clone out or soften the edge of the contact as it doesn't look natural. Processing just looks odd..
I would like to see the original, before it was processed... to get some idea of what is going on.