As the object is three dimensional then there is some depth to it and you should consider how much DOF you need to achieve the effect you want when putting it into a 2D medium.
As DOF was discussed already, taking that and then deciding on the point to focus on depends on the result you want. In general it helps if foreground objects are in focus so in general just focus on the point of the bag that is closest to the camera.
Sometimes to maximise the DOF you can focus behind the closest point as your total DOF is generally 1/3 in front of the focus point and 2/3 behind when using a wide to normal lens and goes to 1/2 - 1/2 as you focus very close or go to telephoto lenses. Just some rules of thumb and you can see the actual numbers when you use a DOF calculator - your example gave you a total of 1.87 feet that will appear in focus. However it is only 1.11 feet from your 5 foot focus point to the back. As it is often easiest to focus on the closest point and you are best off rounding down on distance then you can easily remember f/11 and you have a foot in focus from where you focus to the back (at 5 feet away and at that focal length).
The DOF is dependent as well on the circle of confusion, so the idea is that when using the DOF numbers you will be looking at the final image at a normal viewing distance, if you are zooming in are enlarging the photo and looking at it very close then the amount of area you will see as being in focus will diminish. The solution is often to just look at the picture from a normal distance to evaluate focus.
I do not understand the purpose of the focus lock?
Using the wireless shutter release and the focus and compose method: Best option for me has been to set the AE-L button to AF-ON only. This is the back-button-focus method.
-In this way you will put your focus point on the point you want in focus.
-Push the AE-L button to activate the autofocus and check that focus has been established.
-Release the AE-L button.
-Recompose the scene to have the bag how you want it in the frame.
-Let the camera sit for a second to let vibrations stop.
-Release the shutter using your remote shutter release.
I also have the camera set to AF-C and release priority.
In this method, if you only push the shutter button you do not activate the auto-focus - so it is like you are in manual focus at that point.